4-(4-Methylphenyl)-3-{1-[3-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one CAS 1775547-05-1
| CAS No. | 1775547-05-1 |
| Molecular Formula | C22H21F3N4O2 |
| Molecular Weight | 430.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 430.42 g/mol gives 4-(4-Methylphenyl)-3-{1-[3-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(4-Methylphenyl)-3-{1-[3-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775547-05-1), a certified reference material (molecular formula C22H21F3N4O2, MW 430.42 g/mol) for analytical method development and quality control.
4-(4-Methylphenyl)-3-{1-[3-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (C22H21F3N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Methylphenyl)-3-{1-[3-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H21F3N4O2 |
| Molecular Weight | 430.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methylphenyl Standards
- 4-(4-Methylphenyl)-3-{1-[4-(trifluoromethyl)benzoyl]piperidin-4-yl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775519-41-9)
- {1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazol-4-yl}methyl N-phenylcarbamate (CAS 318247-44-8)
- N-(4-Methylphenyl)-2-[3-oxo-8-(piperidine-1-sulfonyl)-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-2-yl]acetamide (CAS 1779131-88-2)
- {4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl N-(4-chlorophenyl)carbamate (CAS 320424-08-6)
- {1-methyl-5-[(4-methylphenyl)sulfanyl]-3-phenyl-1H-pyrazol-4-yl}methyl 3-methylbenzoate (CAS 318247-63-1)
- 3-(4-Methylphenyl)-5-({[4-(4-methylphenyl)-5-(pyrrolidin-1-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}methyl)-1,2,4-oxadiazole (CAS 920829-44-3)
- 1-(4-Methylphenyl)-4-phenyl-3-({[3-(trifluoromethyl)phenyl]sulfanyl}methyl)azetidin-2-one (CAS 866049-20-9)
- 6-[(4-Ethyl-5-{[(4-methylphenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)methoxy]-2-phenyl-2,3-dihydropyridazin-3-one (CAS 692737-13-6)
Recommended Standards
- (2-(Diphenylphosphino)-1-hydroxyethyl)diphenylphosphine oxide (CAS 65220-79-3)
- 2-[4-(3-Methylpyrazin-2-yl)phenyl]-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide (CAS 1146395-46-1)
- 3-[1-(4-Methylbenzoyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl]propyl 4-methylbenzoate (CAS 318237-85-3)
- 4-[5-(3-Nitrophenyl)-1H-pyrazol-3-yl]-1-{[4-(trifluoromethyl)phenyl]methyl}piperidine (CAS 1030386-16-3)
- 2-(3-(Dimethylamino)pyrrolidin-1-yl)acetic acid hydrate (CAS 1609407-22-8)
- 4-(1-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)aniline (CAS 956263-23-3)
- 5-(2,5-Difluorophenyl)nicotinic acid (CAS 887973-41-3)
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- (2R,6R)-4-(methoxycarbonyl)-6-methylmorpholine-2-carboxylic acid (CAS 2412583-29-8)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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