5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide CAS 452104-85-7
| CAS No. | 452104-85-7 |
| Molecular Formula | C23H27FN4O4 |
| Molecular Weight | 442.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide (CAS 452104-85-7), molecular formula C23H27FN4O4 and molecular weight 442.48 g/mol, is a CATO reference standard with documented purity and traceability.
5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide (C23H27FN4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C23H27FN4O4 |
| Molecular Weight | 442.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Z Standards
- 5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-N-(2-hydroxy-3-morpholinopropyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (CAS 627908-92-3)
- 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-7-methoxy-2-methyl-4H-pyrido[1,2-α]pyrimidin-4-one (CAS 130049-83-1)
- 3-Fluoro-4-((6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinolin-4-yl)oxy)aniline (CAS 960299-67-6)
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-75-5)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618075-97-1)
- 3-(1-((2-Fluoro-[1,1'-biphenyl]-4-yl)oxy)ethyl)-1-((4-fluorophenyl)sulfonyl)-1H-pyrazole (CAS 477711-02-7)
- 3-Fluoro-6-isobutoxy-2,4-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 2377606-11-4)
- 4-Fluoro-N-(1-(4-methoxybenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-90-8)
Recommended Standards
- N-(((9H-fluoren-9-yl)methoxy)carbonyl)-S-(((allyloxy)carbonyl)amino)-L-cysteine (CAS 232953-09-2)
- 4-(Ethoxymethylidene)-2-[4-(morpholine-4-sulfonyl)phenyl]-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 750607-62-6)
- Iloperidone N-Oxide (CAS 1375651-09-4)
- 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1H-pyrrol-2(5H)-one (CAS 618074-95-6)
- 5-((5-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)pyridin-2-amine (CAS 1029052-74-1)
- 2-Chloro-3,4-dimethoxybenzaldehyde (CAS 1065073-93-9)
- 5-Bromo-7,7-dimethyl-7H-benzo[c]fluorene (CAS 954137-48-5)
- 1-amino-2,7-naphthyridine-4-carbonitrile (CAS 2730140-55-1)
- Vitamin A Palmitate (CAS 79-81-2)
- 5-Bromo-2-methylthiophene-3-carbaldehyde (CAS 1369356-10-4)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
- 5-(3,3,3-Trifluoropropoxy)nicotinaldehyde (CAS 1597950-96-3)
- 1,1'-Oxybis[4-((4-nitrophenyl)sulfonyl)]benzene (CAS 54617-07-1)
- Anxiety Peptide (CAS 95237-86-8)
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