2-(4-Bromo-2-fluorophenyl)acetyl chloride CAS 177847-10-8
| CAS No. | 177847-10-8 |
| Molecular Formula | C8H5BrClFO |
| Molecular Weight | 251.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 251.48 g/mol gives 2-(4-Bromo-2-fluorophenyl)acetyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-Bromo-2-fluorophenyl)acetyl chloride (CAS 177847-10-8), a certified reference material (molecular formula C8H5BrClFO, MW 251.48 g/mol) for analytical method development and quality control.
Structurally, 2-(4-Bromo-2-fluorophenyl)acetyl chloride (C8H5BrClFO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 251.48 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClFO |
| Molecular Weight | 251.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-5-fluorophenylacetyl chloride (CAS 1028314-61-5)
- 2-(2-Bromo-4-fluorophenyl)acetyl chloride (CAS 1086601-89-9)
- 2-Bromo-1-(3-chloro-5-fluorophenyl)ethanone (CAS 1207973-38-3)
- 1-(4-Bromo-3-fluorophenyl)-2-chloroethan-1-one (CAS 1260857-14-4)
- 1-(2-Bromo-4-chloro-5-fluorophenyl)ethan-1-one (CAS 129825-10-1)
- 5-Bromo-2-fluorophenylacetyl chloride (CAS 1346146-33-5)
- 2-Bromo-4'-chloro-2-fluoroacetophenone (CAS 1357624-45-3)
- (4-Bromo-3-fluorophenyl)acetyl chloride (CAS 1360868-19-4)
Recommended Standards
- 1-(3-Bromo-2-chloro-6-fluorophenyl)ethan-1-one (CAS 1704367-13-4)
- 1-(4-Bromo-2-chloro-6-fluorophenyl)ethanone (CAS 1823374-59-9)
- 1-(5-Bromo-4-chloro-2-fluorophenyl)ethanone (CAS 1704367-12-3)
- 1-(4-Bromo-2-chloro-3-fluorophenyl)ethan-1-one (CAS 1898158-31-0)
- 3-(4-Fluorophenyl)-1-oxa-2,4,8-triazaspiro[4.5]dec-2-ene (CAS 1713463-19-4)
- 6-Chloro-N-hexylpyrazin-2-amine (CAS 1340168-26-4)
- 2,4-Diethylbenzene-1,3,5-triol (CAS 55380-53-5)
- 2-(3-Methoxyphenyl)nicotinaldehyde (CAS 958219-62-0)
- 2-Methyl-5-chloro-6-benzoxazolamine (CAS 323579-00-6)
- 3-Iodo-1H-pyrrolo[3,2-b]pyridin-7-amine (CAS 1190311-12-6)
- Methyl 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-3-carboxylate (CAS 1303968-44-6)
- Nona-2,4,6-trienal (CAS 56269-22-8)
- 4,9-Dichloro-1-nitroacridine (CAS 75586-66-2)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
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