1-(5-Bromo-4-chloro-2-fluorophenyl)ethanone CAS 1704367-12-3
| CAS No. | 1704367-12-3 |
| Molecular Formula | C8H5BrClFO |
| Molecular Weight | 251.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Bromo-4-chloro-2-fluorophenyl)ethanone (CAS 1704367-12-3), molecular formula C8H5BrClFO and molecular weight 251.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Bromo-4-chloro-2-fluorophenyl)ethanone (C8H5BrClFO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(5-Bromo-4-chloro-2-fluorophenyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClFO |
| Molecular Weight | 251.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-5-fluorophenylacetyl chloride (CAS 1028314-61-5)
- 2-(2-Bromo-4-fluorophenyl)acetyl chloride (CAS 1086601-89-9)
- 2-Bromo-1-(3-chloro-5-fluorophenyl)ethanone (CAS 1207973-38-3)
- 1-(4-Bromo-3-fluorophenyl)-2-chloroethan-1-one (CAS 1260857-14-4)
- 1-(2-Bromo-4-chloro-5-fluorophenyl)ethan-1-one (CAS 129825-10-1)
- 5-Bromo-2-fluorophenylacetyl chloride (CAS 1346146-33-5)
- 2-Bromo-4'-chloro-2-fluoroacetophenone (CAS 1357624-45-3)
- (4-Bromo-3-fluorophenyl)acetyl chloride (CAS 1360868-19-4)
Recommended Standards
- 1-(4-Bromo-3-chloro-2-fluorophenyl)ethan-1-one (CAS 1690794-26-3)
- 1-(3-Bromo-2-chloro-6-fluorophenyl)ethan-1-one (CAS 1704367-13-4)
- 1-(4-Bromo-5-chloro-2-fluorophenyl)ethan-1-one (CAS 1594605-40-9)
- 2-(4-Bromo-2-fluorophenyl)acetyl chloride (CAS 177847-10-8)
- 5-Iodo-3-methyl-1H-indazole (CAS 1180526-40-2)
- 1-(sec-Butyl)-5-methyl-1H-pyrazole (CAS 1171392-51-0)
- tert-Butyl 4-amino-4-(3-(trifluoromethyl)benzyl)piperidine-1-carboxylate (CAS 1774904-88-9)
- 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide (CAS 183321-69-9)
- (1s,6s)-3-Azabicyclo[4.1.0]heptane-1-carboxylic acid hydrochloride (CAS 1485394-89-5)
- 1-(Pyridin-3-yl)cyclopentane-1-carbonitrile (CAS 143619-68-5)
- 4-Methyl-N-(quinoxalin-6-yl)benzamide (CAS 551931-33-0)
- 2-Methyl-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine (CAS 5778-85-8)
- 2-(5-methyl-1,3,4-oxadiazol-2-yl)acetic acid (CAS 937684-91-8)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com