7-Bromo-3-hydroxy-2-naphthoic Acid CAS 1779-11-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1779-11-9
Molecular FormulaC11H7BrO3
Molecular Weight267.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Bromo-3-hydroxy-2-naphthoic Acid CAS 1779-11-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 267.08 g/mol gives 7-Bromo-3-hydroxy-2-naphthoic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

7-Bromo-3-hydroxy-2-naphthoic Acid (CAS 1779-11-9), molecular formula C11H7BrO3 and molecular weight 267.08 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 7-Bromo-3-hydroxy-2-naphthoic Acid (C11H7BrO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H7BrO3
Molecular Weight267.08 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentBr-containing

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