Vonoprazan Impurity 215 CAS 1993-03-9
| CAS No. | 1993-03-9 |
| Molecular Formula | C6H6BFO2 |
| Molecular Weight | 139.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vonoprazan Impurity 215 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Vonoprazan Impurity 215 (CAS 1993-03-9) is a certified pharmaceutical impurity reference standard with the molecular formula C6H6BFO2 and a molecular weight of 139.92 g/mol.
Structurally, Vonoprazan Impurity 215 (C6H6BFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 139.92 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C6H6BFO2 |
| Molecular Weight | 139.92 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Vonoprazan Standards
- Vonoprazan Impurity 133 (CAS 15128-82-2)
- Vonoprazan Fumarate Impurity 56 (CAS 445-27-2)
- Vonoprazan Impurity 139 (CAS CATO-C4X-1020139)
- Vonoprazan Impurity 140 (CAS 208984-17-2)
- Vonoprazan Fumarate Impurity 15 (CAS 636-73-7)
- Vonoprazan Impurity 153 (CAS 15103-48-7)
- Vonoprazan Impurity 154 (CAS 5402-20-0)
- Vonoprazan Impurity N3 (CAS 15177-57-8)
Recommended Standards
- 4-Fluorophenylboronic acid (CAS 1765-93-1)
- Yttrium hydroxide, 99.99% (CAS 16469-22-0)
- 2-Hydroxypyrimidine-5-boronic Acid (CAS 373384-19-1)
- (2,4-Dimethylfuran-3-yl)boronic acid (CAS 1289207-52-8)
- Sitagliptin Impurity 37 (CAS 486459-98-7)
- Varenicline Impurity 33 (CAS CATO-C4X-196233)
- Finerenone Impurity 5 (CAS 2640280-82-4)
- 4-Amino-5,6-dichloropyrimidine (CAS 310400-38-5)
- Tert-butyl (2R,5S)-2-(bromomethyl)-5-methylmorpholine-4-carboxylate (CAS 2440199-05-1)
- 2-Amino-4-chlorobenzoyl chloride (CAS 1261818-40-9)
- (R)-2-Amino-4-phosphonobutanoic acid (CAS 78739-01-2)
- 2-Fluoro-3-(methoxycarbonyl)benzeneboronic acid pinacol ester, 97% (CAS 1638847-77-4)
- N-Ethyl-N-methyl-4-nitroaniline (CAS 56269-48-8)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
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