2-Chloro-5-(difluoromethyl)thiazole CAS 1781434-39-6
| CAS No. | 1781434-39-6 |
| Molecular Formula | C4H2ClF2NS |
| Molecular Weight | 169.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-(difluoromethyl)thiazole (CAS 1781434-39-6) is a high-purity analytical reference standard with the molecular formula C4H2ClF2NS and a molecular weight of 169.58 g/mol.
Structurally, 2-Chloro-5-(difluoromethyl)thiazole (C4H2ClF2NS) contains a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 169.58 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5-(difluoromethyl)thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2ClF2NS |
| Molecular Weight | 169.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 7-Chloro-4-fluoro-1H-indole (CAS 1000341-60-5)
- 4-Chloro-7-fluoro-1h-indole (CAS 1000341-78-5)
- 4-Chloro-2-fluoro-5-methylbenzonitrile (CAS 1126424-34-7)
- 4-Chloro-2-fluoro-3-methylbenzonitrile (CAS 1207875-88-4)
- 6-Chloro-5-fluoro-1H-indole (CAS 122509-72-2)
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- 2-Chloro-2-(2-fluorophenyl)acetonitrile (CAS 1247740-42-6)
- 5-Chloro-2-fluoro-1H-indole (CAS 1354220-70-4)
Recommended Standards
- 2-Chloro-6-fluoro-4-methylbenzonitrile (CAS 1715912-82-5)
- 2-Chloro-3-fluoro-6-methylbenzonitrile (CAS 1805041-90-0)
- 5-Chloro-6-fluoro-1H-indole (CAS 169674-57-1)
- 3-Chloro-2-fluoro-4-methylbenzonitrile (CAS 1805113-33-0)
- N-(2-Chloro-4-nitrophenyl)-2-((4-(4-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332163-95-8)
- (2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)dimethylphosphine oxide (CAS 2444346-79-4)
- 1-(4-methylpyridin-3-yl)piperazine (CAS 1340387-26-9)
- 2,2'-((Pyridin-3-ylmethyl)azanediyl)diacetic acid (CAS 40811-76-5)
- Sulfasalazine (CAS 599-79-1)
- Ziprasidone Impurity 35 (CAS CATO-C4X-124035)
- 6-(trifluoromethyl)naphthalene-1-carboxylic acid (CAS 1261534-88-6)
- Mirabegron Impurity 136 (CAS CATO-C4X-1032136)
- 2-(5-(Furan-2-yl)-2-oxo-1,3,4-oxadiazol-3(2h)-yl)acetic acid (CAS 877825-69-9)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
Why CATO?
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