Chlorambucil EP Impurity G CAS 178481-89-5
| CAS No. | 178481-89-5 |
| Molecular Formula | C14H19Cl2NO2 |
| Molecular Weight | 304.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 304.21 g/mol gives Chlorambucil EP Impurity G distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Chlorambucil EP Impurity G (CAS 178481-89-5), molecular formula C14H19Cl2NO2 and molecular weight 304.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Chlorambucil EP Impurity G (C14H19Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Chlorambucil EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H19Cl2NO2 |
| Molecular Weight | 304.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorambucil Standards
- Meta-Chlorambucil (CAS 134862-11-6)
- Chlorambucil (CAS 305-03-3)
- Chlorambucil Impurity 2 (CAS 94086-78-9)
- Chlorambucil EP Impurity A (CAS 27171-89-7)
- Chlorambucil ethyl ester (CAS 64977-24-8)
- Chlorambucil EP Impurity B (CAS 116505-53-4)
- Chlorambucil EP Impurity D (CAS 94236-91-6)
- Chlorambucil Sodium Salt (CAS 1030-06-4)
Recommended Standards
- 4-(3,5-Dinitrophenoxy)benzoic acid (CAS 168839-42-7)
- 2,5-Dichloro-n-(3-hydroxy-2-methylpropyl)thiophene-3-sulfonamide (CAS 1797163-16-6)
- 4-Bromo-3,5-difluoro-2-((trimethylsilyl)ethynyl)aniline (CAS 1467060-37-2)
- tert-Butyl N-(3,4-dichlorophenyl)-N-propylcarbamate (CAS 1881291-20-8)
- Fedratinib Impurity 1 (CAS 50609-01-3)
- N1,N1-Bis(furan-2-ylmethyl)adipamide (CAS 61190-71-4)
- 4-(4-Amino-2-methylphenoxy)-phenol (CAS 1450906-16-7)
- (R)-3-(4-fluorophenyl)pyrrolidine (CAS 1048703-18-9)
- N-Benzyl-N-(4-methyloxazol-2-yl)acetamide (CAS 57068-04-9)
- Ethyl 3-(1-Boc-4-piperidinyl)butanoate (CAS 203662-40-2)
- Phosphorodithioic acid, zinc salt (CAS 19210-06-1)
- 4-Bromo-2-ethoxy-1-(trifluoromethoxy)benzene (CAS 1355247-61-8)
- Cariprazine Impurity 10 (CAS 506427-91-4)
- Insulin aspart (CAS 116094-23-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com