Chlorambucil EP Impurity D CAS 94236-91-6
| CAS No. | 94236-91-6 |
| Molecular Formula | C16H22Cl3NO2 |
| Molecular Weight | 366.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 366.71 g/mol gives Chlorambucil EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Chlorambucil EP Impurity D (CAS 94236-91-6) is a high-purity analytical reference standard with the molecular formula C16H22Cl3NO2 and a molecular weight of 366.71 g/mol.
The molecular framework of Chlorambucil EP Impurity D (C16H22Cl3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Chlorambucil EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H22Cl3NO2 |
| Molecular Weight | 366.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorambucil Standards
- Chlorambucil ethyl ester (CAS 64977-24-8)
- Chlorambucil Impurity 2 (CAS 94086-78-9)
- Meta-Chlorambucil (CAS 134862-11-6)
- Chlorambucil EP Impurity G (CAS 178481-89-5)
- Chlorambucil (CAS 305-03-3)
- Chlorambucil EP Impurity A (CAS 27171-89-7)
- Chlorambucil EP Impurity C (CAS CATO-C4X-35541)
- Chlorambucil EP Impurity B (CAS 116505-53-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com