4'-fluorospiro[azetidine-3,1'-indane] CAS 1785318-78-6
| CAS No. | 1785318-78-6 |
| Molecular Formula | C11H18FN |
| Molecular Weight | 183.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4'-fluorospiro[azetidine-3,1'-indane].
CATO supplies 4'-fluorospiro[azetidine-3,1'-indane] (CAS 1785318-78-6), a certified reference material (molecular formula C11H18FN, MW 183.27 g/mol) for analytical method development and quality control.
4'-fluorospiro[azetidine-3,1'-indane] (C11H18FN) contains a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4'-fluorospiro[azetidine-3,1'-indane] meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18FN |
| Molecular Weight | 183.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluorospiro Standards
- 6'-fluorospiro[azetidine-3,1'-indane] (CAS 1782046-47-2)
- 6'-fluorospiro[cyclopropane-1,3'-indoline]-2'-one (CAS 1378834-16-2)
- 7'-fluorospiro[cyclopropane-1,3'-indoline]-2'-one (CAS 872141-30-5)
- 6'-Fluorospiro[cyclopropane-1,1'-isoindolin]-3'-one (CAS 1440520-01-3)
- 5'-Fluorospiro[cyclopropane-1,1'-isoindolin]-3'-one (CAS 1440520-03-5)
- 4'-Fluorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 913720-11-3)
- 5’-Fluorospiro[cyclopropane-1,3’-indolin]-2’-one (CAS 769965-95-9)
- 6'-Fluorospiro[cyclopentane-1,3'-indoline] (CAS 1545620-80-1)
Recommended Standards
- 5-Ethyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-amine (CAS 17899-49-9)
- 1-(thian-4-yl)-1H-pyrazol-3-amine (CAS 1781538-18-8)
- N-((1-methyl-1H-imidazol-2-yl)methyl)thietan-3-amine (CAS 1856444-18-2)
- 4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine (CAS 17386-09-3)
- 2-(Aminomethyl)-1,4-dioxane (CAS 88277-83-2)
- 2,5-Dichlorophenyl Glycidyl Ether (CAS 21324-87-8)
- 2-(4-Bromophenyl)-3-(pyrrolidin-1-yl)propanoic acid (CAS 1226314-45-9)
- Guan-fu base A (CAS 1394-48-5)
- 2-{[4-phenyl-5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 18199-82-1)
- Methyl 3-(2-nitrophenyl)-2-oxopropanoate (CAS 79547-07-2)
- 2-(O-tolylthio)ethan-1-amine (CAS 54771-47-0)
- N-methylethylenediamine (CAS 109-81-9)
- 3-Methoxy-5-(4-methoxyphenyl)-1H-1,2,4-triazole (CAS 62036-06-0)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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