Ketoprofen EP Impurity J CAS 1785759-59-2
| CAS No. | 1785759-59-2 |
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ketoprofen EP Impurity J (CAS 1785759-59-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H18O3 and a molecular weight of 282.33 g/mol.
Based on its molecular formula C18H18O3, Ketoprofen EP Impurity J contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 282.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
Related Ketoprofen Standards
- Ketoprofen Ethyl Ester (CAS 60658-04-0)
- Ketoprofen Impurity 78 (CAS 136656-97-8)
- Ketoprofen Impurity 106 (CAS 59310-31-5)
- Ketoprofen-13CD3 Methyl Ester (CAS 1190007-27-2)
- Ketoprofen-d3 Methyl Ester (CAS 1189950-12-6)
- Ketoprofen Impurity 31 (CAS 23323-37-7)
- Ketoprofen Impurity 102 (CAS CATO-C4X-1471102)
- Ketoprofen Impurity 51 (CAS 144977-91-3)
Recommended Standards
- Dapoxetine Impurity 33 (CAS CATO-C4X-143933)
- Propafenone Hydrochloride EP Impurity C (CAS CATO-C4X-132238)
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- 1-(2-hydroxyphenyl)-3-phenylhexane-1,5-dione (CAS CATO-C4X-178110)
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- Mirabegron Impurity 57 (CAS 2184223-32-1)
- Methyl 2-(hydroxymethyl)-3-oxocyclobutane-1-carboxylate (CAS 1824131-33-0)
- 4-Chloro-2-(chloromethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine (CAS 88203-17-2)
- JWH-250 Impurity 2 (JWH 250 5-Hydroxyindole Metabolite) (CAS 1379604-67-7)
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- 1,3-Dichloro-2-fluoro-4-iodobenzene (CAS 1807089-38-8)
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