Propafenone Hydrochloride EP Impurity C CAS CATO-C4X-132238
| CAS No. | CATO-C4X-132238 |
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.33 g/mol gives Propafenone Hydrochloride EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Propafenone Hydrochloride EP Impurity C (CAS CATO-C4X-132238) is a certified pharmaceutical impurity reference standard with the molecular formula C18H18O3 and a molecular weight of 282.33 g/mol.
Structurally, Propafenone Hydrochloride EP Impurity C (C18H18O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 282.33 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Propafenone Standards
- Propafenone EP Impurity C (CAS 22525-95-7)
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
- Propafenone RC 6 (CAS 189766-45-8)
- Propafenone EP Impurity D (CAS 91401-73-9)
- Propafenone EP Impurity E (CAS 165279-79-8)
- Propafenone Impurity 39 (CAS CATO-C4X-132239)
- Propafenone Impurity 40 (CAS CATO-C4X-132240)
- Propafenone Impurity 31 (CAS CATO-C4X-132231)
Recommended Standards
- Dapoxetine Impurity 33 (CAS CATO-C4X-143933)
- Bisoprolol Impurity 48 (CAS 1416440-64-6)
- Ketoprofen EP Impurity J (CAS 1785759-59-2)
- 898764-15-3 Ethyl 4-(3-phenylpropanoyl)benzoate DTXSID60643972 (CAS 898764-15-3)
- Rivastigmine EP Impurity G (CAS 23308-82-9)
- Mupirocin Calcium EP Impurity H (CAS CATO-C4X-170625)
- Zopiclone Impurity 15 (CAS 4180-30-7)
- Etizolam Impurity 20 (CAS 50508-61-7)
- Ethyl 2-(2-bromo-6-cyano-4-methylphenyl)acetate (CAS 1804907-97-8)
- Dimethyl 5-(4-(tert-butyl)phenyl)-1H,3H-pyrrolo[1,2-c]thiazole-6,7-dicarboxylate 2,2-dioxide (CAS 337920-88-4)
- N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N'-propylsulfamide (CAS 1393813-42-7)
- 5-Chloro-2,3-dimethoxyisonicotinaldehyde (CAS 1305324-66-6)
- Methyl 3-((5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)oxy)propanoate (CAS 1346697-67-3)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com