Propafenone EP Impurity C CAS 22525-95-7
| CAS No. | 22525-95-7 |
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Propafenone EP Impurity C is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Propafenone EP Impurity C (CAS 22525-95-7) is a certified pharmaceutical impurity reference standard with the molecular formula C18H18O3 and a molecular weight of 282.33 g/mol.
Owing to a steroid core, a hydroxyl group, an ether linkage, Propafenone EP Impurity C is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Propafenone EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18O3 |
| Molecular Weight | 282.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Propafenone Standards
- Propafenone Hydrochloride EP Impurity C (CAS CATO-C4X-132238)
- Propafenone Impurity 23 (CAS CATO-C4X-132223)
- Propafenone RC 6 (CAS 189766-45-8)
- Propafenone EP Impurity D (CAS 91401-73-9)
- Propafenone EP Impurity E (CAS 165279-79-8)
- Propafenone Impurity 39 (CAS CATO-C4X-132239)
- Propafenone Impurity 40 (CAS CATO-C4X-132240)
- Propafenone Impurity 31 (CAS CATO-C4X-132231)
Recommended Standards
- Bisoprolol Impurity 48 (CAS 1416440-64-6)
- 898764-15-3 Ethyl 4-(3-phenylpropanoyl)benzoate DTXSID60643972 (CAS 898764-15-3)
- Dapoxetine Impurity 33 (CAS CATO-C4X-143933)
- 861439-58-9 3-[(2-Allylphenoxy)methyl]-4-methoxybenzaldehyde MFCD03030302 (CAS 861439-58-9)
- Fluralaner impurity 44 (CAS 1655515-91-5)
- Nerandomilast impurity 2 (CAS CATO-C4X-34732)
- Pinaverium impurity 34 (CAS 1970218-63-3)
- (2E)-2-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-2,3,4,9-tetrahydro-1H-carbazol-1-one (CAS 860612-48-2)
- 4-Cyano-N-cyclopropylpiperidine-1-carboxamide (CAS 1341909-00-9)
- (4-Chloro-1-ethyl-1h-pyrazol-3-yl)methanol (CAS 1310379-55-5)
- 4-Amino-6-(methylthio)-2-((phenylthio)methyl)pyrimidine-5-carbonitrile (CAS 265314-47-4)
- 4,6-Bis(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ol (CAS 681839-63-4)
- tert-Butyl (2-chloropyrimidin-4-yl)(methyl)carbamate (CAS 181363-19-9)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com