Atrasentan Impurity 7 CAS 178608-09-8
| CAS No. | 178608-09-8 |
| Molecular Formula | 2*C27H34N2O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 482.58 g/mol gives Atrasentan Impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Atrasentan Impurity 7 (CAS 178608-09-8), a pharmacopoeial impurity reference standard (molecular formula C27H34N2O6, MW 482.58 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Atrasentan Impurity 7 (C27H34N2O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C27H34N2O6 |
| Molecular Weight | 482.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 2 |
Related Atrasentan Standards
- Atrasentan Impurity 131 (CAS 1058349-04-4)
- Atrasentan Impurity 132 (CAS 1058349-05-5)
- Atrasentan Impurity 133 (CAS 1058349-06-6)
- Atrasentan Impurity 134 (CAS 1058349-07-7)
- Atrasentan Impurity 135 (CAS 1058349-10-2)
- Atrasentan Impurity 136 (CAS 1058349-11-3)
- Atrasentan Impurity 137 (CAS 1058349-12-4)
- Atrasentan Impurity 66 (CAS 1058349-13-5)
Recommended Standards
- Testosterone Impurity 13 (CAS 17305-49-6)
- Atrasentan Impurity 152 (CAS 1058404-01-5)
- Empagliflozin Impurity 134 (CAS CATO-C4X-1065134)
- 3-(Perfluorohexyl)propyl acrylate (CAS 216389-85-4)
- 4-(Methylthio)-2-(trifluoromethyl)benzoic acid (CAS 118939-16-5)
- 5-bromo-7-fluoro-3-nitro-1H-indole (CAS 2758501-36-7)
- 1-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethanone (CAS 1256794-87-2)
- Ethyl 2-((1R,5R)-5-hydroxycyclopent-2-en-1-yl)acetate (CAS 298181-33-6)
- Clofarabine Impurity 4 (CAS CATO-C4X-15934)
- Peptide WE-14 (CAS 115136-18-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com