5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluorothiazol-2-yl)benzenesulfonamide CAS 1788874-30-5
| CAS No. | 1788874-30-5 |
| Molecular Formula | C18H14ClF3N2O4S2 |
| Molecular Weight | 478.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluorothiazol-2-yl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluorothiazol-2-yl)benzenesulfonamide (CAS 1788874-30-5) is a high-purity analytical reference standard with the molecular formula C18H14ClF3N2O4S2 and a molecular weight of 478.89 g/mol.
Structurally, 5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluorothiazol-2-yl)benzenesulfonamide (C18H14ClF3N2O4S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 478.89 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF3N2O4S2 |
| Molecular Weight | 478.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 5-Chloro-N-(3,5-dimethoxybenzyl)-2,4-difluoro-N-(5-fluorothiazol-2-yl)benzenesulfonamide (CAS 2448268-06-0)
- (R)-4-[[3-Chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl]sulfonyl]-N,N-dimethylbenzamide (CAS 252017-04-2)
- 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole (CAS 477710-96-6)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-N-((2-methyl-3-phenylisoxazolidin-5-yl)methyl)methanesulfonohydrazide (CAS 339276-50-5)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N'-[(1E)-[3-(trifluoromethyl)phenyl]methylidene]piperidine-4-carbohydrazide (CAS 338761-42-5)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-(((2,6-dichlorobenzyl)sulfinyl)methyl)-4-methyl-4H-1,2,4-triazole (CAS 344271-85-8)
- 3-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-{[(2,4-dichlorophenyl)methanesulfinyl]methyl}-4-methyl-4H-1,2,4-triazole (CAS 344272-24-8)
- N-(3-chloro-4-methylphenyl)-2-((4-(2,4-dimethylphenyl)-5-(2-hydroxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 831194-08-2)
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