3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole CAS 477710-96-6
| CAS No. | 477710-96-6 |
| Molecular Formula | C22H14ClF3N2O3S |
| Molecular Weight | 478.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole (CAS 477710-96-6), molecular formula C22H14ClF3N2O3S and molecular weight 478.87 g/mol, is a CATO reference standard with documented purity and traceability.
3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole (C22H14ClF3N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-((2,4-difluorophenyl)sulfonyl)-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H14ClF3N2O3S |
| Molecular Weight | 478.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 2-(2-((1-(6-Chloropyridin-2-yl)-1H-1,2,4-triazol-3-yl)methoxy)phenyl)-5-((4-fluorophenoxy)methyl)-1,3,4-oxadiazole (CAS 338756-62-0)
- 1-(4-Bromophenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1404364-58-4)
- n-Ethyl-4-methoxybenzamide (CAS 7403-41-0)
- 1,1'-((4-Methoxyphenyl)methylene)bis(naphthalen-2-ol) (CAS 66595-89-9)
- 6-Boc-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 259809-44-4)
- 2-Benzyl-3-oxo-3-(piperidin-1-yl)propanenitrile (CAS 1148-51-2)
- 4-Amino-8-bromo-N-propylcinnoline-3-carboxamide (CAS 107346-32-7)
- (R)-9-hydroxy-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one (CAS 1190363-44-0)
- 5-Bromo-2,4-dichloro-8-methoxyquinazoline (CAS 1594537-70-8)
- 1-(2,5-Difluorophenyl)-2-((trifluoromethyl)sulfonyl)ethan-1-one (CAS 1346521-35-4)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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