2-Chloro-6-fluorophenylacetyl chloride CAS 179314-61-5
| CAS No. | 179314-61-5 |
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-fluorophenylacetyl chloride (C8H5Cl2FO) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-6-fluorophenylacetyl chloride (CAS 179314-61-5) is a high-purity analytical reference standard with the molecular formula C8H5Cl2FO and a molecular weight of 207.03 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-6-fluorophenylacetyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2FO |
| Molecular Weight | 207.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(3-Chloro-2-fluorophenyl)acetyl chloride (CAS 1040861-09-3)
- 2-Chloro-4-fluoro-3-methylbenzoyl chloride (CAS 1058721-62-2)
- 4-Chloro-2-fluorophenylacetyl chloride (CAS 1159797-03-1)
- 2-Chloro-1-(2-chloro-4-fluorophenyl)ethan-1-one (CAS 1160101-71-2)
- 2-Chloro-5-fluorophenylacetyl chloride (CAS 1175028-47-3)
- 2-Chloro-1-(3-chloro-5-fluorophenyl)ethan-1-one (CAS 1214323-02-0)
- 2-Chloro-1-(2-chloro-5-fluorophenyl)ethan-1-one (CAS 1214391-59-9)
- (2-Chloro-4-fluorophenyl)acetyl chloride (CAS 676348-45-1)
Recommended Standards
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