22-alpha-Hydroxy Cholesterol CAS 17954-98-2
| CAS No. | 17954-98-2 |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 22-alpha-Hydroxy Cholesterol (CAS 17954-98-2), a certified reference material (molecular formula C27H46O2, MW 402.65 g/mol) for analytical method development and quality control.
The molecular framework of 22-alpha-Hydroxy Cholesterol (C27H46O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 22-alpha-Hydroxy Cholesterol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related alpha Standards
- 22-Hydroxy Cholesterol(Mixture of Diastereomers) (CAS 17711-16-9)
- 3β-Hydroxy-5α-cholestan-15-one (CAS 55823-04-6)
- 19-Hydroxy Cholesterol (CAS 561-63-7)
- 22-beta-Hydroxy Cholesterol (CAS 22348-64-7)
- 25-Hydroxy Cholesterol (CAS 2140-46-7)
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- 7β-Hydroxy Cholesterol (CAS 566-27-8)
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Recommended Standards
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