19-Hydroxy Cholesterol CAS 561-63-7
| CAS No. | 561-63-7 |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 19-Hydroxy Cholesterol.
19-Hydroxy Cholesterol (CAS 561-63-7) is a high-purity analytical reference standard with the molecular formula C27H46O2 and a molecular weight of 402.65 g/mol.
The molecular framework of 19-Hydroxy Cholesterol (C27H46O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Hydroxy Standards
- 22-Hydroxy Cholesterol(Mixture of Diastereomers) (CAS 17711-16-9)
- 3β-Hydroxy-5α-cholestan-15-one (CAS 55823-04-6)
- 22-beta-Hydroxy Cholesterol (CAS 22348-64-7)
- 25-Hydroxy Cholesterol (CAS 2140-46-7)
- 7α-Hydroxy Cholesterol (CAS 566-26-7)
- 7β-Hydroxy Cholesterol (CAS 566-27-8)
- 22-alpha-Hydroxy Cholesterol (CAS 17954-98-2)
- 1β-Hydroxy Medroxy Progesterone 17-Acetate (CAS 1072923-65-9)
Recommended Standards
- 4α-Hydroxycholesterol (CAS 34310-86-6)
- Cholesterol Impurity 13 (CAS 34310-88-8)
- 4,4'-Bis(trans-4-propylcyclohexyl)-1,1'-biphenyl (CAS 85600-56-2)
- Cholesterol Impurity 19 (CAS 566-46-1)
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Why CATO?
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