Ganciclovir EP Impurity A CAS 1797982-93-4
| CAS No. | 1797982-93-4 |
| Molecular Formula | C9H10ClN5O2 |
| Molecular Weight | 255.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ganciclovir EP Impurity A (C9H10ClN5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Ganciclovir EP Impurity A (CAS 1797982-93-4) is a certified pharmaceutical impurity reference standard with the molecular formula C9H10ClN5O2 and a molecular weight of 255.66 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ganciclovir EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10ClN5O2 |
| Molecular Weight | 255.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Ganciclovir Standards
- Ganciclovir EP Impurity E (CAS 86357-09-7)
- Ganciclovir EP Impurity H (CAS 84222-50-4)
- Ganciclovir (CAS 82410-32-0)
- Ganciclovir impurity 21 (CAS CATO-C4X-102121)
- Ganciclovir-d5 (CAS 1189966-73-1)
- Ganciclovir Impurity 36 (CAS 86357-10-0)
- Ganciclovir EP Impurity C (CAS 108436-36-8)
- Ganciclovir EP Impurity D (CAS CATO-C4X-10214)
Recommended Standards
- Methyl 2-(3-chloropyridin-2-yl)-5-oxopyrazolidine-3-carboxylate (CAS 774600-50-9)
- Imidacloprid (CAS 138261-41-3)
- Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 832740-93-9)
- (5-(((4-Chloro-3-fluorophenyl)amino)methyl)furan-2-yl)methanol (CAS 1498880-19-5)
- N-Nitroso Felodipine Impurity 23 (CAS CATO-C4X-109423)
- Micafungin Impurity 10 (CAS CATO-C4X-169510)
- Troxerutin Impurity 7 (CAS 862127-01-3)
- 3-(4-Chlorophenyl)oxetan-3-amine (CAS 1245896-06-3)
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- 5-Ethynylbenzo[d][1,3]dioxole (CAS 57134-53-9)
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- 2-Cyano-3-(3,4-dimethylphenyl)propionic Acid (CAS 2044706-99-0)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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