Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate CAS 832740-93-9
| CAS No. | 832740-93-9 |
| Molecular Formula | C10H10ClN3O3 |
| Molecular Weight | 255.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 832740-93-9) is a high-purity analytical reference standard with the molecular formula C10H10ClN3O3 and a molecular weight of 255.66 g/mol.
Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate (C10H10ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 7-(chloromethyl)-5-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClN3O3 |
| Molecular Weight | 255.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Ethyl 5-(chloromethyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 1118787-44-2)
- Methyl 2-(chloromethyl)-7-methoxy-1,3-benzoxazole-5-carboxylate (CAS 1221792-62-6)
- Methyl 2-(chloromethyl)-5-methoxy-1,3-benzoxazole-7-carboxylate (CAS 1221792-89-7)
- 5-(Chloromethyl)-1-(4-fluorophenyl)-1H-1,2,4-triazole-3-carboxylic acid (CAS 1242268-20-7)
- 5-(Chloromethyl)-2-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 1708080-02-7)
- 4-(2-(Chloromethyl)-6-hydroxypyrimidin-4-yl)-1-ethylpyrrolidin-2-one (CAS 1708437-37-9)
- 4-[4-(chloromethyl)-1,3-thiazol-2-yl]-2-methoxyphenol (CAS 926251-43-6)
- (5-(Chloromethyl)furan-2-yl)(4-chlorophenyl)methanone (CAS 2856-02-2)
Recommended Standards
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- Ethyl 2-chloro-8-methoxyimidazo[1,2-b]pyridazine-7-carboxylate (CAS 2577171-74-3)
- Ganciclovir EP Impurity A (CAS 1797982-93-4)
- 2-(Difluoromethyl)-5-hydroxy-3-iodo-6-methoxypyridine (CAS 1805454-84-5)
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- 5-Cyclobutylpyridin-2-amine (CAS 1159814-97-7)
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