Iopamidol Impurity (Desdiiodo Iopamidol) CAS 1798830-49-5
| CAS No. | 1798830-49-5 |
| Molecular Formula | C17H24IN3O8 |
| Molecular Weight | 525.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Iopamidol Impurity (Desdiiodo Iopamidol) (CAS 1798830-49-5), a pharmacopoeial impurity reference standard (molecular formula C17H24IN3O8, MW 525.29 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Iopamidol Impurity (Desdiiodo Iopamidol) (C17H24IN3O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H24IN3O8 |
| Molecular Weight | 525.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iopamidol Standards
- Iopamidol Impurity 35 (CAS CATO-C4X-145035)
- Iopamidol Impurity 29 (CAS 2756222-40-7)
- Iopamidol Impurity 30 (CAS 2756222-41-8)
- Iopamidol Impurity 31 (CAS CATO-C4X-145031)
- Iopamidol Impurity 37 (CAS CATO-C4X-145037)
- Iopamidol Impurity 42 (CAS CATO-C4X-145042)
- Iopamidol Impurity 34 (CAS CATO-C4X-145034)
- Iopamidol Impurity 55 (CAS CATO-C4X-145055)
Recommended Standards
- Dabrafenib Impurity 24 (CAS CATO-C4X-303324)
- (2S,3S,4R,5R)-5-(6-((4-Amino-3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide (CAS 152918-27-9)
- Bis(2-((S)-4-isopropyl-4,5-dihydrooxazol-2-yl)phenyl)dimethylstannane (CAS 823795-88-6)
- Bis(3,5-bis(trifluoromethyl)phenyl)(pyrrolidin-2-yl)methanol (CAS 1139238-28-0)
- Lenvatinib Impurity 71 (CAS 2380197-89-5 (free base))
- Oseltamivir EP Impurity B (CAS 2125702-80-7)
- Capecitabine Impurity 49 (CAS 638-41-5)
- 2-Amino-4-(3-methoxyphenyl)butanoic acid (CAS 225233-76-1)
- Tert-butyl 4-(aminooxy)piperidine-1-carboxylate hydrochloride (CAS 868857-24-3)
- 3-(Piperidin-3-yl)-6-(p-tolyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706456-58-7)
- 2-Bromo-6-(4-(1,1,1-trifluoropropan-2-yl)-4H-1,2,4-triazol-3-yl)pyridine (CAS 2242801-81-4)
- Chlorpromazine Impurity 19 (CAS CATO-C4X-142119)
- tert-Butyl 2-bromo-4,6-dihydro-5H-pyrrolo[3,4-d]thiazole-5-carboxylate (CAS 365996-63-0)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
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