Iopamidol Impurity 29 CAS 2756222-40-7

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.2756222-40-7
Molecular FormulaC8H2Cl3I2NO2
Molecular Weight504.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Iopamidol Impurity 29 CAS 2756222-40-7 chemical structure

Description

The occurrence of Iopamidol Impurity 29 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Iopamidol Impurity 29 (CAS 2756222-40-7), a pharmacopoeial impurity reference standard (molecular formula C8H2Cl3I2NO2, MW 504.27 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Iopamidol Impurity 29 (C8H2Cl3I2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 504.27 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Iopamidol Impurity 29 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H2Cl3I2NO2
Molecular Weight504.27 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity≥95%
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentCl/I-containing
Nitrogen Atoms1

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