Capecitabine Impurity 49 CAS 638-41-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.638-41-5
Molecular FormulaC6H11ClO2
Molecular Weight150.60 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Capecitabine Impurity 49 CAS 638-41-5 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Capecitabine Impurity 49 (CAS 638-41-5), a pharmacopoeial impurity reference standard (molecular formula C6H11ClO2, MW 150.60 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Capecitabine Impurity 49 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 150.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H11ClO2
Molecular Weight150.60 g/mol
Purity>95%
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1957
Halogen ContentCl-containing

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