3-Amino-2-chlorobenzenethiol CAS 1801694-22-3
| CAS No. | 1801694-22-3 |
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-2-chlorobenzenethiol is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-2-chlorobenzenethiol (CAS 1801694-22-3) is a high-purity analytical reference standard with the molecular formula C6H6ClNS and a molecular weight of 159.64 g/mol.
The molecular framework of 3-Amino-2-chlorobenzenethiol (C6H6ClNS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Amino-2-chlorobenzenethiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNS |
| Molecular Weight | 159.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-Amino-4-chlorobenzenethiol (CAS 1004-00-8)
- 4-Amino-3-chlorobenzenethiol (CAS 1122-40-3)
- 2-Amino-6-chlorobenzenethiol (CAS 14482-33-8)
- 4-Amino-2-chlorobenzene-1-thiol (CAS 15178-53-7)
- 2-Amino-3-chlorobenzenethiol (CAS 40925-72-2)
- 2-Amino-5-chlorobenzenethiol (CAS 23474-98-8)
- 5-Amino-2-chlorobenzenethiol (CAS 97094-83-2)
- 4-amino-2-chloro-pyridine-3-carbonitrile (CAS 1194341-42-8)
Recommended Standards
- 5-Chloro-2-cyclopropylthiazole (CAS 1849283-73-3)
- 3-chloro-2-methyl-pyridine-4-thiol (CAS 1851566-28-3)
- 2-Chloro-5-cyclopropylthiazole (CAS 1412953-26-4)
- 2-Chloro-4-cyclopropylthiazole (CAS 1344072-01-0)
- 1-(4-Piperidinyl)-1,2,3,4-tetrahydroquinolinedihydrochloride (CAS 1170419-42-7)
- [(4-bromo-1-methyl-1h-pyrazol-5-yl)methyl](methyl)amine (CAS 1001500-52-2)
- Methyl 4-cyclopropyl-1,2,3-thiadiazole-5-carboxylate (CAS 183303-75-5)
- Methyl 4-amino-3-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)isothiazole-5-carboxylate (CAS 1823182-74-6)
- (S)-Benzyl 4-((2-amino-N-ethyl-3-methylbutanamido)methyl)piperidine-1-carboxylate (CAS 1353995-29-5)
- 139163-56-7 1-(6-Bromo-2-pyridinyl)-1-ethanol MFCD12198456 (CAS 139163-56-7)
- 2-(Trimethylsilyl)ethyl piperazine-1-carboxylate (CAS 219687-93-1)
- 2-(3,4-Dichlorophenyl)-2-methylpropan-1-ol (CAS 80854-13-3)
- N-Nitroso Dalilesen impurity 14 (CAS CATO-C4X-301014)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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