Vortioxetine Impurity 81 CAS 18023-22-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.18023-22-8
Molecular FormulaC8H10O3S
Molecular Weight186.23 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Vortioxetine Impurity 81 CAS 18023-22-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 186.23 g/mol gives Vortioxetine Impurity 81 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Vortioxetine Impurity 81 (CAS 18023-22-8), a pharmacopoeial impurity reference standard (molecular formula C8H10O3S, MW 186.23 g/mol) used for the identification and quantification of trace impurities in APIs.

Vortioxetine Impurity 81 (C8H10O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Vortioxetine Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H10O3S
Molecular Weight186.23 g/mol
Purity>95%
StorageStore at 2-8°C, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Sulfur Atoms1

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