Ticagrelor Impurity 53 CAS 145783-12-6
| CAS No. | 145783-12-6 |
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H10N2O2S, Ticagrelor Impurity 53 contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 186.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Ticagrelor Impurity 53 (CAS 145783-12-6, C7H10N2O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H10N2O2S |
| Molecular Weight | 186.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity N1 (CAS 2227766-79-0)
- Ticagrelor Impurity 78 (CAS 1351990-36-7)
- Ticagrelor Impurity 173 (CAS 1212376-05-0)
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 135 (CAS CATO-C4X-1093135)
- Ticagrelor Impurity 27 (CAS 1444301-60-3)
- Ticagrelor impurity 136 (CAS 1932275-13-2)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
Recommended Standards
- Vortioxetine Impurity 81 (CAS 18023-22-8)
- Racecadotril Impurity 15 (CAS 80-48-8)
- Vonoprazan Impurity 204 (CAS 4810-41-7)
- Acotiamide Impurity 9 (CAS 948053-83-6)
- Zolmitriptan EP Impurity G (CAS CATO-C4X-135123)
- Perindopril Impurity 38 (CAS 80828-13-3)
- Atrasentan Impurity 167 (CAS 1059043-40-1)
- Tivozanib Hydrochloride Monohydrate (CAS 682745-41-1)
- n,n-Dimethyl-4-[(e)-2-(5-phenyl-1,3-benzoxazol-2-yl)ethenyl]aniline (CAS 40442-35-1)
- (2S,4S)-2-Cyclopropylpiperidin-4-ol hydrochloride (CAS 1909288-12-5)
- 2,4-Bis(2-chloroethoxy)benzaldehyde (CAS 325465-62-1)
- 4,4,4-Trifluoro-3-hydroxybutanoic Acid (CAS 86884-21-1)
- sodium 2-methyl-2-(1,3-thiazol-2-yl)propanoate (CAS 2044796-55-4)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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