Baricitinib Impurity 46 HCl CAS 1803583-30-3
| CAS No. | 1803583-30-3 |
| Molecular Formula | C9H7N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 46 HCl (CAS 1803583-30-3, C9H7N5HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H7N5HCl, Baricitinib Impurity 46 HCl contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Baricitinib Impurity 46 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7N5 HCl |
| Molecular Weight | 221.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Baricitinib Standards
- Baricitinib Impurity 21 (CAS 1024120-52-2)
- Baricitinib Impurity 14 (CAS 1029716-44-6)
- Baricitinib Impurity 23 (CAS 1146629-75-5)
- Baricitinib Impurity 39 (CAS 1146629-76-6)
- Baricitinib Impurity 42 (CAS 1146629-77-7)
- Baricitinib Impurity 18 (CAS 1153949-11-1)
- Baricitinib Impurity N5 (CAS 1153949-15-5)
- Baricitinib (CAS 1187594-09-7)
Recommended Standards
- Amlodipine EP Impurity G (CAS 43067-01-2)
- Carbetocin Impurity 40 (CAS CATO-C4X-191140)
- Voglibose Impurity 6 (CAS 38231-86-6)
- 18:1 dimethylacetal (CAS 15677-71-1)
- CRF (6-33) (human, rat) (CAS 120066-38-8)
- 3-(Piperidin-4-ylidene)-2,3-dihydro-1H-indol-2-one (CAS 79099-09-5)
- 3-isothiocyanato-N,N-dimethylpropanamide (CAS 1248198-30-2)
- 5-(Thiophen-3-yl)pentan-2-ol (CAS 1342639-25-1)
- (R)-pentan-2-amine (CAS 33985-20-5)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com