2-Fluoro-6-hydroxy-4-methylphenylboronic acid CAS 1803598-06-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1803598-06-2
Molecular FormulaC7H8BFO3
Molecular Weight169.95 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-6-hydroxy-4-methylphenylboronic acid CAS 1803598-06-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 169.95 g/mol gives 2-Fluoro-6-hydroxy-4-methylphenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Fluoro-6-hydroxy-4-methylphenylboronic acid (CAS 1803598-06-2) is a high-purity analytical reference standard with the molecular formula C7H8BFO3 and a molecular weight of 169.95 g/mol.

The molecular framework of 2-Fluoro-6-hydroxy-4-methylphenylboronic acid (C7H8BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H8BFO3
Molecular Weight169.95 g/mol
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1995
Halogen ContentF-containing

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