3-(Difluoromethoxy)cyclobutane-1-carboxylic acid CAS 1803603-34-0
| CAS No. | 1803603-34-0 |
| Molecular Formula | C6H8F2O3 |
| Molecular Weight | 166.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Difluoromethoxy)cyclobutane-1-carboxylic acid.
3-(Difluoromethoxy)cyclobutane-1-carboxylic acid (CAS 1803603-34-0) is a high-purity analytical reference standard with the molecular formula C6H8F2O3 and a molecular weight of 166.12 g/mol.
Based on its molecular formula C6H8F2O3, 3-(Difluoromethoxy)cyclobutane-1-carboxylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 166.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(Difluoromethoxy)cyclobutane-1-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O3 |
| Molecular Weight | 166.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
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Recommended Standards
- 4,4-Difluoro-3-methyltetrahydrofuran-3-carboxylic acid (CAS 1782346-79-5)
- 2,2-Difluoro-3,3-dihydroxycyclohexanone (CAS 183742-86-1)
- 2,2-Difluoro-2-(tetrahydrofuran-3-yl)acetic acid (CAS 1781025-79-3)
- (1S,3s)-3-(difluoromethoxy)cyclobutane-1-carboxylic acid (CAS 1919865-10-3)
- Open-ring Desulfated Aztreonam Ethyl Ester 2 (CAS CATO-C4X-152237)
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- 4-(2-Fluorobenzyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid (CAS 1043465-80-0)
- 3-Amino-1-(2-methylphenyl)urea (CAS 15940-63-3)
- 2-Sulfamoylthiophene-3-carboxylic acid (CAS 59338-06-6)
- Methyl (2Z)-2-acetamido-3-(2,3,6-trifluorophenyl)prop-2-enoate (CAS 1616502-86-3)
- 1-Propanone, 3,3-dimethoxy-1-(4-methylphenyl)- (CAS 80335-80-4)
- 2,5-Dibromo-4-fluorotoluene (CAS 134332-29-9)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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