3-(difluoromethoxy)phenol CAS 88798-13-4
| CAS No. | 88798-13-4 |
| Molecular Formula | C7H12F2O2 |
| Molecular Weight | 166.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(difluoromethoxy)phenol (C7H12F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 3-(difluoromethoxy)phenol (CAS 88798-13-4), a certified reference material (molecular formula C7H12F2O2, MW 166.17 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(difluoromethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H12F2O2 |
| Molecular Weight | 166.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F-containing |
Related difluoromethoxy Standards
- 6-(difluoromethoxy)pyridin-2-amine (CAS 1131007-43-6)
- 2-(difluoromethoxy)pyridin-4-amine (CAS 1211587-46-0)
- 4-(Difluoromethoxy)cyclohexanol (CAS 1565472-22-1)
- 2-(Difluoromethoxy)cyclohexan-1-ol (CAS 2306269-33-8)
- 6-(difluoromethoxy)pyridin-3-amine (CAS 317810-73-4)
- 3-(Difluoromethoxy)cyclobutane-1-carboxylic acid (CAS 1803603-34-0)
- 3-(Difluoromethoxy)tetrahydro-4H-pyran-4-one (CAS 2141137-50-8)
- trans-4-(Difluoromethoxy)cyclohexanamine (CAS 1403864-40-3)
Recommended Standards
- 3-(4-oxocyclohexyl)prop-2-ynoic acid (CAS 2166921-82-8)
- 3-(Hydroxymethyl)-2-methylbenzoic acid (CAS 277331-16-5)
- 3-(3,4-Dihydroxyphenyl)propanal (CAS 545442-98-6)
- 3-(Hydroxymethyl)-4-methoxybenzaldehyde (CAS 76646-42-9)
- 2-(7-Ethyl-3-methyl-4,5,6,7-tetrahydro-1H-indazol-1-yl)ethanamine (CAS 561299-90-9)
- 4-Ethyl-1H-pyrazolo[4,3-c]pyridine (CAS 1140240-48-7)
- 1-(4-Chlorobenzenesulfonyl)-4-{5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}piperidine (CAS 1025724-67-7)
- Propantheline bromide impurity 1 (CAS 115036-05-0)
- Ethyl 3-(prop-2-en-1-yl)piperidine-3-carboxylate (CAS 170843-46-6)
- Cyanidin 3-O-a-arabinopyranoside chloride (CAS 57186-11-5)
- 1-(3-Ethylcyclopentyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 634586-05-3)
- 5-Isopropoxypyridin-2-amine (CAS 846549-59-5)
- 2,4-Dichloro-3-(4-fluorophenyl)propiophenone (CAS 898768-70-2)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com