4-(Aminomethyl)-3-(cyanomethyl)-6-(difluoromethyl)picolinonitrile CAS 1804697-56-0
| CAS No. | 1804697-56-0 |
| Molecular Formula | C10H8F2N4 |
| Molecular Weight | 222.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Aminomethyl)-3-(cyanomethyl)-6-(difluoromethyl)picolinonitrile (CAS 1804697-56-0), molecular formula C10H8F2N4 and molecular weight 222.19 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H8F2N4, 4-(Aminomethyl)-3-(cyanomethyl)-6-(difluoromethyl)picolinonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F2N4 |
| Molecular Weight | 222.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Aminomethyl Standards
- 2-(Aminomethyl)-3-cyano-4-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805187-34-1)
- 2-(Aminomethyl)-3-cyano-5-(difluoromethyl)pyridine-6-acetonitrile (CAS 1805504-92-0)
- 2-(Aminomethyl)-4-cyano-3-(difluoromethyl)pyridine-5-acetonitrile (CAS 1805981-13-8)
- 2-(Aminomethyl)-6-cyano-3-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806009-30-2)
- 2-(Aminomethyl)-3-cyano-6-(difluoromethyl)pyridine-4-acetonitrile (CAS 1806853-37-1)
- 2-(Aminomethyl)-3-cyano-6-(difluoromethyl)pyridine-5-acetonitrile (CAS 1806853-40-6)
- 4-(Aminomethyl)-5-(cyanomethyl)-2-(difluoromethyl)nicotinonitrile (CAS 1806853-62-2)
- 2-(Aminomethyl)-6-cyano-5-(difluoromethyl)pyridine-3-acetonitrile (CAS 1806957-70-9)
Recommended Standards
- Ethyl 2-(ethoxymethylidene)-4,4-difluoro-3-oxobutanoate (CAS 176969-33-8)
- 2-(2,4-Difluorophenoxy)pyridin-3-amine (CAS 175135-63-4)
- (1R,2R)-4,4-difluoro-2-(methoxycarbonyl)cyclohexane-1-carboxylic acid (CAS 1694638-13-5)
- 6-(3,5-Difluorophenyl)-2-methylpyrimidin-4-ol (CAS 1690654-47-7)
- Allyl sorbate (CAS 7493-75-6)
- 3-(5-Ethylthiophen-2-yl)-3-oxopropanal (CAS 1247528-04-6)
- (+)-Norpropoxyphene maleate (CAS 159208-83-0)
- 1H-Indole-2, 5,7-dichloro- 5,3-dione 5,7-Dichloroisatin 6374-92-1 Indole-2, 5,7-dichloro- Isatin,7-dichloro- MLS002639083 NSC-26045 NSC26045 (CAS 6374-92-1)
- 7-Bromo-1a,2,3,7b-tetrahydro-1H-cyclopropa[c]quinoline (CAS 1404431-48-6)
- [3-(trifluoromethyl)phenyl]methanesulfonamide (CAS 919353-96-1)
- 2-((1-(Thiazol-2-yl)ethyl)amino)acetic acid (CAS 1353986-30-7)
- 2-chloro-4-(trifluoromethyl)pyridin-3-amine (CAS 166770-70-3)
- 1,2,3,4,5,6,7,8-Octahydroacridin-9-amine succinate (CAS 866245-79-6)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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