2-(4-(Difluoromethyl)-6-methoxy-5-nitropyridin-2-yl)acetonitrile CAS 1804870-92-5
| CAS No. | 1804870-92-5 |
| Molecular Formula | C9H7F2N3O3 |
| Molecular Weight | 243.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-(Difluoromethyl)-6-methoxy-5-nitropyridin-2-yl)acetonitrile.
2-(4-(Difluoromethyl)-6-methoxy-5-nitropyridin-2-yl)acetonitrile (CAS 1804870-92-5), molecular formula C9H7F2N3O3 and molecular weight 243.17 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-(Difluoromethyl)-6-methoxy-5-nitropyridin-2-yl)acetonitrile (C9H7F2N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 243.17 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-(Difluoromethyl)-6-methoxy-5-nitropyridin-2-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7F2N3O3 |
| Molecular Weight | 243.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-5-methoxy-3-nitropyridine-4-acetonitrile (CAS 1805068-31-8)
- 2-(4-(Difluoromethyl)-3-methoxy-5-nitropyridin-2-yl)acetonitrile (CAS 1805068-41-0)
- 2-(Difluoromethyl)-3-methoxy-5-nitropyridine-6-acetonitrile (CAS 1805553-38-1)
- 2-(Difluoromethyl)-5-methoxy-4-nitropyridine-3-acetonitrile (CAS 1805553-56-3)
- 2-(4-(Difluoromethyl)-2-methoxy-5-nitropyridin-3-yl)acetonitrile (CAS 1805554-30-6)
- 2-(2-(Difluoromethyl)-6-methoxy-5-nitropyridin-3-yl)acetonitrile (CAS 1805606-23-8)
- 2-(Difluoromethyl)-3-methoxy-5-nitropyridine-4-acetonitrile (CAS 1806035-01-7)
- 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-5-acetonitrile (CAS 1806960-20-2)
Recommended Standards
- Dimethyl 1-methyl-4-nitro-1H-pyrazole-3,5-dicarboxylate (CAS 159427-78-8)
- ((6-Methoxy-5-nitropyrimidin-4-yl)oxy)methyl acetate (CAS 136718-69-9)
- 1-Chloro-4-(chloro(cyclohexyl)methyl)benzene (CAS 100614-59-3)
- (2-bromobenzyl)ethyldimethylaminium (2-bromophenyl)methyl-ethyl-dimethylazanium (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 59-41-6 Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with 4-methylbenzenesulfonic acid (1:1) Bretylium Bretylium tolsylate Bretylium tosylate(USAN) Bretylum D02YYF N-(2-bromobenzyl)-N,N-dimethylethanaminium N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium (CAS 59-41-6)
- 3-Methyl-5-(methylamino)-1,2-thiazole-4-carboxylic acid (CAS 871217-45-7)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with 2-hydroxyethyl 2-propenoate and 2-propenoic acid (CAS 66747-40-8)
- 6-Amino-4,7-dimethyl-2H-chromen-2-one (CAS 29001-25-0)
- (2S,4R)-4-Cyanopyrrolidine-2-carboxylic acid (CAS 273221-93-5)
- N-(4-Fluorophenyl)-9H-fluorene-9-carboxamide (CAS 866155-68-2)
- 1-(3,5-dimethylbenzoyl)piperidin-3-amine (CAS 1305859-79-3)
- Ethyl 2-bromo-4,5,6,7-tetrahydrobenzo[d]thiazole-6-carboxylate (CAS 1547445-11-3)
- Nintedanib Impurity 43 (CAS 59276-28-7)
- 4-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1-methylpiperazine-2-carboxylic acid (CAS 2137506-61-5)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com