2-(2-Bromo-6-cyano-4-(difluoromethyl)pyridin-3-yl)acetic acid CAS 1805357-07-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1805357-07-6
Molecular FormulaC9H5BrF2N2O2
Molecular Weight291.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Bromo-6-cyano-4-(difluoromethyl)pyridin-3-yl)acetic acid CAS 1805357-07-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 2-(2-Bromo-6-cyano-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805357-07-6), a certified reference material (molecular formula C9H5BrF2N2O2, MW 291.05 g/mol) for analytical method development and quality control.

The molecular framework of 2-(2-Bromo-6-cyano-4-(difluoromethyl)pyridin-3-yl)acetic acid (C9H5BrF2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H5BrF2N2O2
Molecular Weight291.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Br-containing
Nitrogen Atoms2

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