6-(Difluoromethyl)-2,3-dimethoxypyridin-4-amine CAS 1806044-32-5
| CAS No. | 1806044-32-5 |
| Molecular Formula | C8H10F2N2O2 |
| Molecular Weight | 204.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Difluoromethyl)-2,3-dimethoxypyridin-4-amine.
6-(Difluoromethyl)-2,3-dimethoxypyridin-4-amine (CAS 1806044-32-5), molecular formula C8H10F2N2O2 and molecular weight 204.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-(Difluoromethyl)-2,3-dimethoxypyridin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 204.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(Difluoromethyl)-2,3-dimethoxypyridin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10F2N2O2 |
| Molecular Weight | 204.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-4-iodo-1H-pyrazole (CAS 1041205-43-9)
- 2-[1-(difluoromethyl)-3,5-dimethyl-1h-pyrazol-4-yl]acetic acid (CAS 1221724-52-2)
- Ethyl 1-(difluoromethyl)-3-methyl-1H-pyrazole-5-carboxylate (CAS 128537-24-6)
- 5-(difluoromethyl)-1-ethyl-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 1384427-73-9)
- Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate (CAS 141573-95-7)
- Ethyl 5-(difluoromethyl)-1-methyl-1H-pyrazole-3-carboxylate (CAS 1437312-22-5)
- Methyl 5-(difluoromethyl)-1-ethyl-1H-pyrazole-4-carboxylate (CAS 1443287-95-3)
- 5-(Difluoromethyl)-3,4-dimethoxypyridin-2-amine (CAS 1804451-51-1)
Recommended Standards
- (2-Amino-5-(difluoromethyl)-6-methoxypyridin-3-yl)methanol (CAS 1805970-62-0)
- 2-(Difluoromethyl)-3,6-dimethoxypyridin-4-amine (CAS 1806044-65-4)
- (2-Amino-3-(difluoromethyl)-5-methoxypyridin-4-yl)methanol (CAS 1805970-53-9)
- (4-Amino-6-(difluoromethyl)-5-methoxypyridin-2-yl)methanol (CAS 1806793-46-3)
- (E)-3-(2-hydroxy-3-methoxyphenyl)acrylic acid (CAS 1081760-29-3)
- 3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aniline hydrochloride (CAS 1803599-82-7)
- 2-(Aminomethyl)-3-(cyclopropylmethoxy)phenol (CAS 1243347-69-4)
- Carfilzomib Impurity 25 (CAS CATO-C4X-102225)
- 5-fluoro-7-methoxy-tetralin-1-one (CAS 837373-16-7)
- 2,3,4,5-Tetrahydro-1H-1-benzazepine-2-carboxylic acid (CAS 1367678-37-2)
- 3-Fluorocyclobutanol (CAS 1380170-67-1)
- 1-(4-Bromophenyl)-3-((4-(sec-butyl)phenyl)amino)propan-1-one (CAS 882748-25-6)
- 5-(1-Allyl-2-oxoindolin-3-ylidene)-2-(4-ethoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 538340-83-9)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
Why CATO?
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