2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride CAS 1806975-93-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1806975-93-8
Molecular FormulaC8H5ClF3NO2
Molecular Weight239.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride CAS 1806975-93-8 chemical structure

Description

The occurrence of 2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride (CAS 1806975-93-8), molecular formula C8H5ClF3NO2 and molecular weight 239.58 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C8H5ClF3NO2, 2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 239.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-6-fluoro-3-methoxypyridine-5-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5ClF3NO2
Molecular Weight239.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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