1,2-Dichloro-4-(difluoromethoxy)-5-methylbenzene CAS 1807052-48-7
| CAS No. | 1807052-48-7 |
| Molecular Formula | C8H6Cl2F2O |
| Molecular Weight | 227.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1,2-Dichloro-4-(difluoromethoxy)-5-methylbenzene (CAS 1807052-48-7), a certified reference material (molecular formula C8H6Cl2F2O, MW 227.04 g/mol) for analytical method development and quality control.
Structurally, 1,2-Dichloro-4-(difluoromethoxy)-5-methylbenzene (C8H6Cl2F2O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 227.04 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,2-Dichloro-4-(difluoromethoxy)-5-methylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2F2O |
| Molecular Weight | 227.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 1,2-Dichloro-4-(difluoromethoxy)-3-methylbenzene (CAS 1803833-82-0)
- (2,6-Dichloro-3-(difluoromethyl)pyridin-4-yl)methanamine (CAS 1805281-61-1)
- 2,5-Dichloro-1-(difluoromethoxy)-3-methylbenzene (CAS 1806302-03-3)
- 1,3-Dichloro-5-(difluoromethoxy)-2-methylbenzene (CAS 1807038-51-2)
- 2',4-Dichloro-2,4'-bipyrimidine (CAS 2589638-88-8)
- 2,4-Dichloro-6-(pyridin-2-yl)-1,3,5-triazine (CAS 339547-32-9)
- 5,5-Dichloro-6-hydroxy-1,3-dimethyldihydropyrimidine-2,4(1H,3H)-dione (CAS 50610-50-9)
- 5,7-Dichloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 848401-00-3)
Recommended Standards
- 2-(2,4-Dichlorophenyl)-2,2-difluoroethan-1-ol (CAS 1823847-79-5)
- 3-Chloro-4-(chloromethyl)-5-(difluoromethyl)pyridin-2-amine (CAS 1806831-31-1)
- 2-(2,6-Dichlorophenyl)-2,2-difluoroethan-1-ol (CAS 1824000-39-6)
- 3-Chloro-6-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine (CAS 1806809-80-2)
- 1-(2,3-Dihydroxybenzyl)piperidin-4-one (CAS 831223-62-2)
- N-(4-Acetylphenyl)-4-ethyl-5-methylthiophene-3-carboxamide (CAS 895933-27-4)
- 4,4,6,6-Tetramethyl-1,3,2-dioxaborinan-2-ol (CAS 104562-46-1)
- 4-((4-((2-(4-Nitrophenyl)-2-oxoethoxy)carbonyl)phenyl)amino)-4-oxobutanoic acid (CAS 774557-89-0)
- ((1R,1'r,4R,4'R)-4'-ethyl-[1,1'-bi(cyclohexan)]-4-yl)methyl methanesulfonate (CAS 819862-02-7)
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