Methyl 2-hydroxy-3,5-diiodobenzoate CAS 18071-50-6
| CAS No. | 18071-50-6 |
| Molecular Formula | C8H6I2O3 |
| Molecular Weight | 403.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-hydroxy-3,5-diiodobenzoate (CAS 18071-50-6) is a high-purity analytical reference standard with the molecular formula C8H6I2O3 and a molecular weight of 403.94 g/mol.
The molecular framework of Methyl 2-hydroxy-3,5-diiodobenzoate (C8H6I2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6I2O3 |
| Molecular Weight | 403.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | I-containing |
Related Methyl Standards
- 2-Hydroxy-3,5-diiodobenzohydrazide (CAS 89011-15-4)
- 4-Hydroxy-3,5-diiodobenzohydrazide (CAS 89011-17-6)
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Recommended Standards
- 3-(2-Chlorobenzyl)-6,7-dimethoxy-2-(propylthio)quinazolin-4(3H)-imine (CAS 860610-74-8)
- 3,5-Diiodo-2-methoxybenzoic acid (CAS 19094-55-4)
- 3-(2-Chlorobenzyl)-2-(isopropylthio)-6,7-dimethoxyquinazolin-4(3H)-imine (CAS 860610-73-7)
- 3,5-Diiodo-4-hydroxyphenylacetic Acid (CAS 1948-39-6)
- (4-Chloro-3-methoxypyridin-2-yl)methyl acetate (CAS 409098-84-6)
- 3-Chloro-N,N-diethylpyrazin-2-amine (CAS 1249331-91-6)
- (3,4-Dichlorophenyl)(6-methylpyridin-2-yl)methanone (CAS 1187170-00-8)
- 8-Chloro-2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indole hydrochloride (CAS 3785-12-4)
- 1-ethyl-5-[2-(trimethylsilyl)ethynyl]-1H-pyrazole (CAS 1707563-64-1)
- N-methoxycarbonyl-o-methylisourea (CAS 40943-37-1)
- Methyl 2-(4-chlorophenoxy)benzoate (CAS 25958-83-2)
- 2-[(2-Amino-6-chlorophenyl)disulfanyl]-3-chloroaniline (CAS 155909-29-8)
- 3-Amino-1-benzylpiperidin-2-one (CAS 209983-73-3)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
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