N-[3-[(5-Methoxy-3-indolyl)methylene]-2-oxo-5-indolinyl]-3-(1-piperidinyl)propanamide CAS 181223-80-3
| CAS No. | 181223-80-3 |
| Molecular Formula | C26H28N4O3 |
| Molecular Weight | 444.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[3-[(5-Methoxy-3-indolyl)methylene]-2-oxo-5-indolinyl]-3-(1-piperidinyl)propanamide.
CATO supplies N-[3-[(5-Methoxy-3-indolyl)methylene]-2-oxo-5-indolinyl]-3-(1-piperidinyl)propanamide (CAS 181223-80-3), a certified reference material (molecular formula C26H28N4O3, MW 444.53 g/mol) for analytical method development and quality control.
The molecular framework of N-[3-[(5-Methoxy-3-indolyl)methylene]-2-oxo-5-indolinyl]-3-(1-piperidinyl)propanamide (C26H28N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[3-[(5-Methoxy-3-indolyl)methylene]-2-oxo-5-indolinyl]-3-(1-piperidinyl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H28N4O3 |
| Molecular Weight | 444.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 4 |
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Why CATO?
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