5,6-Diethyl-3-hydroxypyrazine-2-carboxamide CAS 181284-16-2

Description

The occurrence of 5,6-Diethyl-3-hydroxypyrazine-2-carboxamide is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5,6-Diethyl-3-hydroxypyrazine-2-carboxamide (CAS 181284-16-2), molecular formula C9H13N3O2 and molecular weight 195.22 g/mol, is a CATO reference standard with documented purity and traceability.

5,6-Diethyl-3-hydroxypyrazine-2-carboxamide (C9H13N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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