5-Bromo-3-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione CAS 81077-92-1
| CAS No. | 81077-92-1 |
| Molecular Formula | C11H9BrN2O2S |
| Molecular Weight | 313.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Bromo-3-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (CAS 81077-92-1), a certified reference material (molecular formula C11H9BrN2O2S, MW 313.17 g/mol) for analytical method development and quality control.
5-Bromo-3-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (C11H9BrN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Bromo-3-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9BrN2O2S |
| Molecular Weight | 313.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- N-(5-Bromo-3-pyridyl)benzenesulfonamide, 97% (CAS 1084-12-4)
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Recommended Standards
- 5-((4-Bromophenyl)sulfonyl)pyridin-2-amine, 97% (CAS 909532-22-5)
- 6-Bromo-2-(methylsulfinyl)-8,9-dihydroimidazo[1',2':1,6]pyrido[2,3-d]pyrimidine (CAS 2761069-97-8)
- 4-Bromo-N-(pyridin-4-yl)benzenesulfonamide (CAS 3763-34-6)
- Methyl 4-amino-3-(4-bromophenyl)isothiazole-5-carboxylate (CAS 82424-60-0)
- 3-Cyclopropoxy-4-methoxy-N-methylpicolinamide (CAS 1243449-42-4)
- 1-Hydroxy-7-nitroanthracene-9,10-dione (CAS 52808-13-6)
- (3aR,8aR)-Tetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-N,N-bis[(1R)-1-phenylethyl]-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-amine (CAS 1226495-37-9)
- Tert-butyl (1-(3,4-dichlorophenyl)-3-hydroxypropyl)carbamate (CAS 936497-86-8)
- 4-Formyl-2-methoxybenzenesulfonamide (CAS 1289126-13-1)
- 3’-(Trifluoromethoxy)acetanilide (CAS 1956-85-0)
- (R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid (CAS 32222-45-0)
- Ethyl 2-fluoro-6-methoxyisonicotinate (CAS 1804494-12-9)
- Ceritinib Impurity 22 (CAS CATO-C4X-104822)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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