Carvedilol impurity 8 CAS 18181-71-0
| CAS No. | 18181-71-0 |
| Molecular Formula | C9H12O3 |
| Molecular Weight | 168.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Carvedilol impurity 8 (CAS 18181-71-0), a pharmacopoeial impurity reference standard (molecular formula C9H12O3, MW 168.19 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Carvedilol impurity 8 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 168.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Carvedilol impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12O3 |
| Molecular Weight | 168.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Carvedilol Standards
- Carvedilol Impurity 5 (CAS 1836-62-0)
- Carvedilol Impurity 20 (CAS 72955-82-9)
- Carvedilol impurity 15 (CAS 52602-39-8)
- Carvedilol Impurity 23 (CAS 206647-27-0)
- Carvedilol Impurity 24 (CAS 42988-85-2)
- Carvedilol USP Related Compound D (CAS 51997-51-4)
- Carvedilol Impurity 4 (CAS 72955-96-5)
- Carvedilol impurity 17 (CAS 123119-89-1)
Recommended Standards
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- Trimethylphloroglucinol (CAS 4463-03-0)
- Ketoprofen Impurity 31 (CAS 23323-37-7)
- Valsartan Impurity 5 ·xHCl (CAS CATO-C4X-105785)
- Blonanserin Impurity 30 (CAS CATO-C4X-111030)
- 5-(2-Chlorophenyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 26029-13-0)
- UK 370106 (CAS 230961-21-4)
- Methyl 3-(2-aminothiazol-5-yl)propanoate (CAS 883501-73-3)
- ethyl 7-bromo-4-oxo-pyrido[1,2-a]pyrimidine-3-carboxylate (CAS 16867-56-4)
- Diacetyl 2,4-Dinitrophenylhydrazone (CAS 2256-00-0)
- 5-((1H-1,2,4-Triazol-3-yl)thio)-2-nitroaniline (CAS 55564-45-9)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com