Carvedilol Impurity 24 CAS 42988-85-2
| CAS No. | 42988-85-2 |
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Carvedilol Impurity 24 (CAS 42988-85-2, C10H16N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Carvedilol Impurity 24 (C10H16N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 196.25 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Carvedilol Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16N2O2 |
| Molecular Weight | 196.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 2 |
Related Carvedilol Standards
- Carvedilol Impurity 23 (CAS 206647-27-0)
- Carvedilol impurity 15 (CAS 52602-39-8)
- Carvedilol Impurity 20 (CAS 72955-82-9)
- Carvedilol impurity 8 (CAS 18181-71-0)
- Carvedilol Impurity 5 (CAS 1836-62-0)
- Carvedilol USP Related Compound D (CAS 51997-51-4)
- Carvedilol Impurity 4 (CAS 72955-96-5)
- Carvedilol impurity 17 (CAS 123119-89-1)
Recommended Standards
- Clavulanate Potassium EP Impurity C (CAS 86917-74-0)
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- Sildenafil Impurity 54 (CAS 133261-07-1)
- Cyclo(-Pro-Val) (CAS 2854-40-2)
- Luliconazole impurity 30 (CAS CATO-C4X-285330)
- Salmeterol EP Impurity B (CAS 94749-02-7)
- Milnacipran Impurity N13 (CAS 105310-75-6)
- 2-Chloro-3-nitro-5-(trifluoromethoxy)pyridine (CAS 1361842-46-7)
- 4-(3,5-Difluorophenyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1272271-77-8)
- (1-Methyl-1H-indol-5-yl)methanamine (CAS 884507-17-9)
- Methyl 2-oxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate (CAS 884001-27-8)
- 8-Methyl-1-naphthaleneboronic Acid (CAS 948592-91-4)
- 5-((3,5-Dimethyl-4-nitro-1h-pyrazol-1-yl)methyl)furan-2-carboxylic acid (CAS 380580-59-6)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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