Raloxifene Impurity 20 CAS 182133-38-6

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.182133-38-6
Molecular FormulaC15H12O4S2
Molecular Weight320.38 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Raloxifene Impurity 20 CAS 182133-38-6 chemical structure

Description

The occurrence of Raloxifene Impurity 20 is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Raloxifene Impurity 20 (CAS 182133-38-6), a pharmacopoeial impurity reference standard (molecular formula C15H12O4S2, MW 320.38 g/mol) used for the identification and quantification of trace impurities in APIs.

Raloxifene Impurity 20 (C15H12O4S2) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Raloxifene Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H12O4S2
Molecular Weight320.38 g/mol
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2009
Sulfur Atoms2

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