2-(((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)difluoromethyl)thio)acetic acid CAS 1823183-77-2
| CAS No. | 1823183-77-2 |
| Molecular Formula | C10H5ClF5N3O2S |
| Molecular Weight | 361.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)difluoromethyl)thio)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)difluoromethyl)thio)acetic acid (CAS 1823183-77-2), a certified reference material (molecular formula C10H5ClF5N3O2S, MW 361.68 g/mol) for analytical method development and quality control.
Structurally, 2-(((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)difluoromethyl)thio)acetic acid (C10H5ClF5N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 361.68 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(((8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)difluoromethyl)thio)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF5N3O2S |
| Molecular Weight | 361.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-(4-Chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)-2,2-dimethylpropan-1-one (CAS 2390149-19-4)
- 5-Chloro-2,3-dihydro-2-oxo-6-benzoxazolyl β-D-Glucopyranosiduronic Acid (CAS 87620-03-9)
- N-{2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoroethyl}-N-methyl-N-nitroguanidine (CAS 1823194-81-5)
- (3-Chloro-4-((3,4-dichlorobenzyl)oxy)-5-ethoxyphenyl)methanol (CAS 678158-52-6)
- 2-Butyl-4-chloro-5-((2,4-dichlorobenzyl)oxy)pyridazin-3(2H)-one (CAS 88094-29-5)
- 7-Chloro-5-fluoro-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3-benzoxazole (CAS 866010-51-7)
- 1-(2-Chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylic acid (CAS 1243023-71-3)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-methoxypropyl)-1H-pyrrole-2-carboxamide (CAS 338397-69-6)
Recommended Standards
- N-allyl-2-chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]acetamide (CAS 924133-96-0)
- Copper(II) trifluoromethanesulfonate 34946-82-2 COPPER TRIFLATE;COPPER(II) TRIFLATE;COPPER(II) TRIFLUOROMETHANESULFONATE;COPPER(II) TRIFLUOROMETHANESULPHONATE;CU(OTF)2;CUPRIC TRIFLUOROMETHANESULFONATE;TRIFLUOROMETHANESULFONIC ACID COPPER SALT;TRIFLUOROMETHANESULFONIC ACID COPPER(II) SALT SC10047 (CAS 34946-82-2)
- 3-[2,5-Bis(chloromethyl)-4-methoxy-phenoxy]propane-1-sulfonyl chloride (CAS 118943-26-3)
- 1-(3-(4-Bromo-2-chlorophenoxy)propyl)-4-ethylpiperazine (CAS 1704081-38-8)
- (2-methyl-4-nitrophenyl)methanol (CAS 22162-15-8)
- 1-(3-Bromo-5-hydroxyphenyl)ethan-1-one (CAS 867366-86-7)
- (S)-2-Amino-2-(3-bromophenyl)acetic acid (CAS 2088419-03-6)
- (1S)-1-(p-tolyl)ethanamine (CAS 27298-98-2)
- Crisaborole lmpurity 82 (CAS CATO-C4X-202182)
- 1-(3-Methylbutan-2-yl)-1h-pyrazole-3-carboxylic acid (CAS 1306607-12-4)
- 3-Bromo-2-cyclopropoxy-N-methylaniline (CAS 1243393-33-0)
- cvxIAA (CAS 2127037-35-6)
- Ulipristal Impurity 11 (CAS CATO-C4X-191511)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com