Cimetidine EP Impurity H CAS 74886-59-2
| CAS No. | 74886-59-2 |
| Molecular Formula | C10H18N8S2 |
| Molecular Weight | 314.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cimetidine EP Impurity H is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cimetidine EP Impurity H (CAS 74886-59-2), a pharmacopoeial impurity reference standard (molecular formula C10H18N8S2, MW 314.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H18N8S2, Cimetidine EP Impurity H contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 314.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Cimetidine EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H18N8S2 |
| Molecular Weight | 314.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 2 |
Related Cimetidine Standards
- Cimetidine impurity 26 (CAS 208447-53-4)
- Cimetidine Impurity 14 (CAS CATO-C4X-158914)
- Cimetidine impurity 29 (CAS CATO-C4X-158929)
- Cimetidine EP Impurity C (CAS 77076-18-7)
- Cimetidine EP Impurity A (CAS 52378-40-2)
- Cimetidine EP Impurity E (CAS 54237-72-8)
- Cimetidine Impurity 12 (CAS 75850-09-8)
- Cimetidine impurity 27 (CAS CATO-C4X-158927)
Recommended Standards
- N-benzyl-4-methyl-2-(thiophen-3-yl)thiazole-5-carboxamide (CAS 949256-10-4)
- Thiamine Impurity 32 (CAS 52164-53-1)
- N-(Benzo[d]thiazol-5-yl)-4-(ethylthio)benzamide (CAS 942002-90-6)
- Thiamine /Vitamin B1 Impurity 56 (CAS 1153-39-5)
- Drotaverin Impurity 72 (CAS CATO-C4X-243572)
- Imatinib Impurity 59 (CAS 220213-15-0)
- Dexlansoprazole Impurity 5 (CAS CATO-C4X-161245)
- 2,5-Dichloro-3,6-dimethylaniline (CAS 81742-11-2)
- Azetidin-1-yl(phenyl)methanone (CAS 3420-62-0)
- 2,6-Dichloro-N-(1-methyl-1H-imidazol-4-yl)pyrimidin-4-amine (CAS 1208893-80-4)
- 6-Chloro-4-iodobenzo[d]thiazol-2-amine (CAS 1702854-56-5)
- (-)-Corynantheidine (CAS 23407-35-4)
- 1-Stearoyl-rac-glycerol (CAS 123-94-4)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com