Prucalopride Impurity 9 CAS 182808-16-8
| CAS No. | 182808-16-8 |
| Molecular Formula | C9H9ClN2O2 |
| Molecular Weight | 212.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Prucalopride Impurity 9 (CAS 182808-16-8) is a certified pharmaceutical impurity reference standard with the molecular formula C9H9ClN2O2 and a molecular weight of 212.63 g/mol.
The molecular framework of Prucalopride Impurity 9 (C9H9ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9ClN2O2 |
| Molecular Weight | 212.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Prucalopride Standards
- Prucalopride Impurity 23 (CAS 123654-26-2)
- Prucalopride Impurity 17 (CAS 932114-06-2)
- Prucalopride Impurity 7 (CAS 129511-06-4)
- Prucalopride Impurity 46 (CAS 182808-04-4)
- Prucalopride Impurity 25 (CAS 149466-67-1)
- Prucalopride Impurity 29 (CAS 24190-77-0)
- Prucalopride Impurity 28(Cisapride Impurity) (CAS 38059-73-3)
- Prucalopride Impurity 12 (CAS 179474-79-4)
Recommended Standards
- N-allyl-5-chloro-2-nitroaniline (CAS 524034-30-8)
- (E)-3-(2-chlorophenoxy)but-2-enoic acid (CAS CATO-C4X-344117)
- N1-(2-Chlorophenyl)-N2-methyloxalamide (CAS 423728-41-0)
- Fenbufen 4-Chlorophenyl Butanoic Acid (CAS 3984-34-7)
- Itraconazole Impurity 64 (CAS 2570971-58-1)
- Benzoic Acid Impurity 2 (CAS 775304-03-5)
- Etoricoxib Impurity 6 (CAS 221615-75-4)
- 2-[1-(5-Fluoropyridin-2-yl)-1H-pyrazol-4-yl]ethanol (CAS 1269382-44-6)
- 3,5-PIperidinedione (CAS 769070-04-4)
- 5-(p-Tolyl)-1,3,4-oxadiazole-2-carbaldehyde (CAS 944897-88-5)
- ethyl 5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-carboxylate (CAS 1379526-96-1)
- Trazodone EP Impurity K (CAS 6969-71-7)
- 5-Aminouridine HCl salt (CAS 116154-74-6)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com