Prucalopride Impurity 29 CAS 24190-77-0
| CAS No. | 24190-77-0 |
| Molecular Formula | C10H10ClNO4 |
| Molecular Weight | 243.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 243.64 g/mol gives Prucalopride Impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Prucalopride Impurity 29 (CAS 24190-77-0, C10H10ClNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H10ClNO4, Prucalopride Impurity 29 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Prucalopride Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO4 |
| Molecular Weight | 243.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Prucalopride Standards
- Prucalopride Impurity 28(Cisapride Impurity) (CAS 38059-73-3)
- Prucalopride Impurity 25 (CAS 149466-67-1)
- Prucalopride Impurity 23 (CAS 202664-85-5)
- Prucalopride Impurity 18 (CAS 338791-13-2)
- Prucalopride Impurity 46 (CAS 182808-04-4)
- Prucalopride Impurity 27 (CAS CATO-C4X-103827)
- Prucalopride Impurity 14 (CAS CATO-C4X-103814)
- Prucalopride Impurity 17 (CAS 932114-06-2)
Recommended Standards
- Baclofen impurity 4 (CAS 159112-23-9)
- Metoclopramide Impurity 12 (CAS 24201-13-6)
- 712286-89-0 3-[(Chloroacetyl)amino]-4-methoxybenzoic acid MFCD04069097 (CAS 712286-89-0)
- Procaine Impurity 24 (CAS CATO-C4X-262324)
- Pregabalin Impurity 54 (CAS 616-42-2)
- Perampanel Impurity 1 (CAS 381248-06-2)
- Fasudil Impurity 32 (CAS 116970-50-4)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2,2,2-trifluoroethoxy)pyridine (CAS 1073354-46-7)
- 2-(4-amino-3-methylbenzenesulfonyl)ethan-1-ol (CAS 1566347-08-7)
- (2S,4S)-4-amino-8-azaspiro[4.5]Decan-2-ol dihydrochloride (CAS 2306246-52-4)
- 3'-Amino-[1,1'-biphenyl]-4-carboxylic acid hydrochloride (CAS 257876-76-9)
- 3-Chloro-2-nitrobenzyl chloride (CAS 1261642-82-3)
- 1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethan-1-one (CAS 1422065-15-3)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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