1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS 182869-10-9
| CAS No. | 182869-10-9 |
| Molecular Formula | C22H19F4N3O3 |
| Molecular Weight | 449.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-10-9) is a high-purity analytical reference standard with the molecular formula C22H19F4N3O3 and a molecular weight of 449.40 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 449.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H19F4N3O3 |
| Molecular Weight | 449.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorophenyl Standards
- 1-(2,4-Difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-08-5)
- 5-{bis[(3,4-difluorophenyl)methyl]amino}-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 957040-67-4)
- 2-(3,4-Difluorophenyl)-4-((3-methylbut-2-en-1-yl)oxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 890306-94-2)
- 2-(3,4-Difluorophenyl)-4-((3-methylbut-3-en-1-yl)oxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 890306-92-0)
- N-(2,4-Difluorophenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775421-30-1)
- N-(2,5-Difluorophenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775510-60-5)
- N-(2,4-difluorophenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040633-88-2)
- 8-(2,6-Difluorophenyl)-2-((1,3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 444606-18-2)
Recommended Standards
- Apalutamide Impurity 109 (CAS CATO-C4X-2749109)
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- (R)-2-((S)-2-(2-(2-(1,3-Dioxoisoindolin-2-yl)ethoxy)acetamido)propanamido)pentanedioic acid (CAS 142489-47-2)
- 2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-4,5-diphenyl-1-(prop-2-yn-1-yl)-1H-imidazole (CAS 339277-25-7)
- 8-Chloro-5-fluorochroman-4-one (CAS 1092350-94-1)
- 3,5-Dibromo-2-methylisonicotinaldehyde (CAS 2504230-92-4)
- [1,1'-Biphenyl]-2-yl(4-(dimethylamino)phenyl)(methyl)phosphineoxide (CAS 94861-77-5)
- (R)-3-((tert-Butoxycarbonyl)amino)-4-(2-cyanophenyl)butanoic acid (CAS 269726-80-9)
- 4-(4-Methoxybenzoyl)-N-((tetrahydrofuran-2-yl)methyl)-1H-pyrrole-2-carboxamide (CAS 478259-15-3)
- tert-butyl 4-mercaptopiperidine-1-carboxylate (CAS 134464-79-2)
- 3-(3-(Methylsulfonyl)phenyl)pyridine (CAS 160777-42-4)
- 1-cyclohexanecarbonylazetidine-3-carboxylic acid (CAS 1342089-18-2)
- 1-Propyl-1H-pyrazole-3-carbonitrile (CAS 1245773-20-9)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
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