Avanafil Impurity 48 CAS 1830294-64-8
| CAS No. | 1830294-64-8 |
| Molecular Formula | C23H24ClN7O4 |
| Molecular Weight | 497.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C23H24ClN7O4, Avanafil Impurity 48 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 497.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Avanafil Impurity 48 (CAS 1830294-64-8), a pharmacopoeial impurity reference standard (molecular formula C23H24ClN7O4, MW 497.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24ClN7O4 |
| Molecular Weight | 497.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Avanafil Standards
- Avanafil Impurity 51 (CAS CATO-C4X-111851)
- Avanafil Impurity 120 (CAS CATO-C4X-1118120)
- Avanafil Impurity 122 (CAS CATO-C4X-1118122)
- Avanafil Impurity 147 (CAS CATO-C4X-1118147)
- Avanafil Impurity 29 (CAS CATO-C4X-111829)
- Avanafil Impurity 60 (CAS CATO-C4X-111860)
- Avanafil Impurity 61 (CAS CATO-C4X-111861)
- Avanafil Impurity 154 (CAS CATO-C4X-1118154)
Recommended Standards
- 3-(4-Chlorophenoxy)-8-((diisobutylamino)methyl)-7-hydroxy-2-(trifluoromethyl)-4H-chromen-4-one (CAS 685861-37-4)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(4-(4-methoxyphenyl)piperazin-1-yl)ethan-1-one (CAS 338979-18-3)
- 1-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonyl)-4-phenylpiperazine (CAS 344277-92-5)
- 2,4-Dibromo-6-{[(5-iodo-3-methylpyridin-2-yl)amino]methyl}phenol (CAS 672949-84-7)
- Tamsulosin EP Impurity D (CAS 1799280-05-9)
- Levofloxacin EP Impurity G(Levofloxacin USP Related Compound E) (CAS 151250-76-9)
- Chlorpromazine EP Impurity B DiHCl (CAS 19077-20-4)
- N-Isobutyl-5,6-dihydro-4H-1,3-thiazin-2-amine (CAS 179116-10-0)
- 4-chloro-5,7-dimethylpyrrolo[2,1-f][1,2,4]triazine-6-carbonitrile (CAS 2092848-43-4)
- (R)-2-(3,4-dichlorophenyl)piperidine (CAS 1241682-95-0)
- 6-Bromo-2-fluoro-3-nitrobenzyl bromide (CAS 1807255-98-6)
- 6-chloro-3-methyl-pyrimidin-4-one (CAS 101079-62-3)
- 1-Benzyl-4-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1172783-48-0)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
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